[(1S,3S,4S)-4-氨基-3-羟基-5-苯基-1-(苯甲基)戊基]-氨基甲酸叔丁酯

[(1S,3S,4S)-4-氨基-3-羟基-5-苯基-1-(苯甲基)戊基]-氨基甲酸叔丁酯 - Names and Identifiers

Name	Carbamic acid,[(1s,2s,4s)-4-amino-3-Hydroxy-5-phenyl-1-phenylmethyl]pentyl-1,1-dimethylethyl ester
Synonyms	BDH (2S,3S,5S)-2-amino-3-hydroxy-5-(t-butyloxycarbonylamino- tert-butyl (2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-ylcarbamate tert-butyl [(2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl]carbamate (2S,3S,5S)-5-(Tert-butoxybonyl) amino-2-amino-3-hydroxy-1,6-diphenylhexane (2S,3S,5S)-2-aMino-3-hydroxy-5-(t-butyloxycarbonylaMino)-1,6-diphenylhexane [(1S,3S,4S)-4-AMino-3-hydroxy-5-phenyl-1-(phenylMethyl)pentyl]carbaMic acid (2S,3S,5S)-5-tert-butyloxycarbonylamino-2-amino-3-hydroxy-1,6-diphenylhexane (2S,3S,5S)-5-(Tert-butyloxycarbonyl)amino-2-amino-3-hydroxy-1,6-diphenyl hexane (2S,3S,5S)-5-(Tert-butyloxycarbonyl)amino-2-amino-3-hydroxy-1,6-diphenyl hexane (BDH) (2S,3S,5S)-2-Amino-3-Hydroxy-5(T)-Butyloxycarbonylamino-1,6-Diphenyl-HexaneSuccinicAcid (2S,3S,5S)-2-amino-3-hydroxy-5-(t-butyloxycarbonylamino-1,6-diphenyl-hexane succinic acid (2S,3S,5S)-2-Amino-3-Hydroxy-5-(Tert-Butyloxycarbonylamino)-1,6-Diphenyl Hexane Succinic Acid Carbamic acid,[(1s,2s,4s)-4-amino-3-Hydroxy-5-phenyl-1-phenylmethyl]pentyl-1,1-dimethylethyl ester [(1S,3S,4S)-4-Amino-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]carbamic acid 1,1-dimethylethyl ester [(1S,3S,4S)-4-Amino-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-carbamic acid 1,1-dimethylethyl ester [(1s,3s,4s)-4-amino-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-carbamic acid 1,1-dimethylethyl ester
CAS	144163-85-9
EINECS	685-103-4
InChI	InChI=1/C23H32N2O3/c1-23(2,3)28-22(27)25-19(14-17-10-6-4-7-11-17)16-21(26)20(24)15-18-12-8-5-9-13-18/h4-13,19-21,26H,14-16,24H2,1-3H3,(H,25,27)/t19-,20-,21-/m0/s1

[(1S,3S,4S)-4-氨基-3-羟基-5-苯基-1-(苯甲基)戊基]-氨基甲酸叔丁酯 - Physico-chemical Properties

Molecular Formula	C23H32N2O3
Molar Mass	384.51
Density	1.110
Melting Point	71-74°C
Boling Point	569.2±50.0 °C(Predicted)
Flash Point	298.03°C
Vapor Presure	0mmHg at 25°C
pKa	12.35±0.46(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,2-8°C
Refractive Index	1.562

[(1S,3S,4S)-4-氨基-3-羟基-5-苯基-1-(苯甲基)戊基]-氨基甲酸叔丁酯 - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed

[(1S,3S,4S)-4-氨基-3-羟基-5-苯基-1-(苯甲基)戊基]-氨基甲酸叔丁酯 - Introduction

Carbamic acid,[(1S, 2S, 4s)-pentyl-1,1-dimethylethyl ester, also known as N-tert-butyryl chloride-(1S,3S,4S)-3-Hydroxy-4-phenyl-1-benzyl-2-aminopentanoic acid tert-butyl ester. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-The molecular formula of the compound is C26H35ClN2O3 and the molecular weight is 461.032g/mol.
-It is a solid, common in the form of white crystals.
-The compound is a hydrophobic solid, soluble in alcohol, ether and most organic solvents, insoluble in water.

Use:
-Carbamic,[(1S, 2S, 4s)-pentyl-1], 1-dimethylethyl ester is a chiral reagent, commonly used as a reducing agent in organic synthesis, catalyst or chiral resolution reagent.
-It can participate in the synthesis of biologically active compounds.
-The compound can also be used in the field of pharmaceutical research, such as the synthesis of anti-cancer drugs.

Method:
-Carbamic,[(1S, 2S, 4s)-1] pentyl-1, the preparation method of 1-dimethylethyl ester is relatively complicated, usually requiring multi-step reactions.
-One of the commonly used preparation methods is synthesis by hydrogenation catalyzed by chiral asymmetric catalysts.

Safety Information:
-Carbamic,[(1S, 2S, 4s)-but] pentyl-1, 1-dimer ethyl ester should be handled with caution, and appropriate safety procedures should be followed during operation.
-This compound may be irritating to the eyes, skin and respiratory system, so avoid contact when using it. Wear appropriate protective equipment such as gloves, masks and safety glasses during operation.
-In addition, ensure that the operation is carried out in a well-ventilated place to avoid inhaling dust or gas.
-If you contact or inhale the compound by accident, you should immediately seek help from medical personnel and bring the packaging container or label.

Please note that the above information is for reference only. Before using the compound or performing related operations, please carefully read and follow the safety data sheet and instructions for use of the relevant chemical, and consult a professional if necessary.

Last Update：2024-04-09 20:52:54